De E-klasse Coupé van Mercedes-Benz is een 2-deurs coupé en is sinds 1993 leverbaar. Dit model is leverbaar als 2,0 tot 3,5-liter diesel of benzine. De vanafprijs begint bij €56.176 voor de E 200 Coupé en lopen op tot €82.412 voor best uitgeruste model, de E 350 d 4MATIC Coupé.
| Type | Motor | Transmissie | Inhoud |
| E 200 Coupé | benzine | 9G-Tronic 9 | 2.0 liter |
| E 300 Coupé | benzine | 9G-Tronic 9 | 2.0 liter |
| E 400 4MATIC Coupé | benzine | 9G-Tronic 9 | 3.5 liter |
| E 220 d Coupé | diesel | 9G-Tronic 9 | 2.0 liter |
| E 220 d 4MATIC Coupé | diesel | 9G-Tronic 9 | 2.0 liter |
| E 350 d 4MATIC Coupé | diesel | 9G-Tronic 9 | 3.0 liter |
| Type | Motor | Transmissie | Inhoud |
| E 200 Coupé | benzine | handm. 6 | 2.0 liter |
| E 200 Coupé Ambition | benzine | handm. 6 | 2.0 liter |
| E 200 Coupé Prestige | benzine | handm. 6 | 2.0 liter |
| E 200 Coupé | benzine | 7G-Tronic 7 | 2.0 liter |
| E 200 Coupé Ambition | benzine | 7G-Tronic 7 | 2.0 liter |
| E 200 Coupé Sport Edition | benzine | 7G-Tronic 7 | 2.0 liter |
| E 200 Coupé Prestige | benzine | 7G-Tronic 7 | 2.0 liter |
| E 250 Coupé | benzine | 7G-Tronic 7 | 2.0 liter |
| E 250 Coupé Ambition | benzine | 7G-Tronic 7 | 2.0 liter |
| E 250 Coupé Sport Edition | benzine | 7G-Tronic 7 | 2.0 liter |
| E 250 Coupé Prestige | benzine | 7G-Tronic 7 | 2.0 liter |
| E 320 Coupé | benzine | 7G-Tronic 7 | 3.0 liter |
| E 320 Coupé Ambition | benzine | 7G-Tronic 7 | 3.0 liter |
| E 320 Coupé Sport Edition | benzine | 7G-Tronic 7 | 3.0 liter |
| E 320 Coupé Prestige | benzine | 7G-Tronic 7 | 3.0 liter |
| E 400 Coupé | benzine | 7G-Tronic 7 | 3.0 liter |
| E 400 Coupé Ambition | benzine | 7G-Tronic 7 | 3.0 liter |
| E 400 Coupé Prestige | benzine | 7G-Tronic 7 | 3.0 liter |
| E 300 Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 300 Coupé Ambition | benzine | 7G-Tronic 7 | 3.5 liter |
| E 300 Coupé Prestige | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 Coupé Ambition | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 Coupé Prestige | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 4Matic Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 4Matic Coupé Ambition | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 4Matic Coupé Prestige | benzine | 7G-Tronic 7 | 3.5 liter |
| E 400 Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 400 Coupé Ambition | benzine | 7G-Tronic 7 | 3.5 liter |
| E 400 Coupé Sport Edition | benzine | 7G-Tronic 7 | 3.5 liter |
| E 400 Coupé Prestige | benzine | 7G-Tronic 7 | 3.5 liter |
| E 500 Coupé | benzine | 7G-Tronic 7 | 4.7 liter |
| E 500 Coupé Ambition | benzine | 7G-Tronic 7 | 4.7 liter |
| E 500 Coupé Prestige | benzine | 7G-Tronic 7 | 4.7 liter |
| E 220 CDI Coupé | diesel | handm. 6 | 2.1 liter |
| E 220 CDI Coupé Ambition | diesel | handm. 6 | 2.1 liter |
| E 220 d Coupé | diesel | handm. 6 | 2.1 liter |
| E 220 d Coupé Ambition | diesel | handm. 6 | 2.1 liter |
| E 220 CDI Coupé Prestige | diesel | handm. 6 | 2.1 liter |
| E 220 d Coupé Prestige | diesel | handm. 6 | 2.1 liter |
| E 250 CDI Coupé | diesel | handm. 6 | 2.1 liter |
| E 250 d Coupé | diesel | handm. 6 | 2.1 liter |
| E 250 CDI Coupé Ambition | diesel | handm. 6 | 2.1 liter |
| E 250 d Coupé Ambition | diesel | handm. 6 | 2.1 liter |
| E 250 CDI Coupé Prestige | diesel | handm. 6 | 2.1 liter |
| E 250 d Coupé Prestige | diesel | handm. 6 | 2.1 liter |
| E 220 CDI Coupé | diesel | 7G-Tronic 7 | 2.1 liter |
| E 220 d Coupé | diesel | 9G-Tronic 9 | 2.1 liter |
| E 220 CDI Coupé Ambition | diesel | 7G-Tronic 7 | 2.1 liter |
| E 220 d Coupé Ambition | diesel | 9G-Tronic 9 | 2.1 liter |
| E 220 d Coupé Sport Edition | diesel | 9G-Tronic 9 | 2.1 liter |
| E 220 CDI Coupé Prestige | diesel | 7G-Tronic 7 | 2.1 liter |
| E 220 d Coupé Prestige | diesel | 9G-Tronic 9 | 2.1 liter |
| E 250 CDI Coupé | diesel | 7G-Tronic 7 | 2.1 liter |
| E 250 d Coupé | diesel | 9G-Tronic 9 | 2.1 liter |
| E 250 CDI Coupé Ambition | diesel | 7G-Tronic 7 | 2.1 liter |
| E 250 d Coupé Ambition | diesel | 9G-Tronic 9 | 2.1 liter |
| E 250 d Coupé Sport Edition | diesel | 9G-Tronic 9 | 2.1 liter |
| E 250 CDI Coupé Prestige | diesel | 7G-Tronic 7 | 2.1 liter |
| E 250 d Coupé Prestige | diesel | 9G-Tronic 9 | 2.1 liter |
| E 350 BlueTEC Coupé | diesel | 7G-Tronic 7 | 3.0 liter |
| E 350 BlueTEC Coupé Ambition | diesel | 7G-Tronic 7 | 3.0 liter |
| E 350 BlueTEC Coupé Prestige | diesel | 7G-Tronic 7 | 3.0 liter |
| E 350 d Coupé | diesel | 9G-Tronic 9 | 3.0 liter |
| E 350 d Coupé Ambition | diesel | 9G-Tronic 9 | 3.0 liter |
| E 350 d Coupé Sport Edition | diesel | 9G-Tronic 9 | 3.0 liter |
| E 350 d Coupé Prestige | diesel | 9G-Tronic 9 | 3.0 liter |
| Type | Motor | Transmissie | Inhoud |
| E 200 CGI BlueEFFICIENCY Coupé | benzine | handm. 6 | 1.8 liter |
| E 200 BlueEFFICIENCY Coupé | benzine | handm. 6 | 1.8 liter |
| E 200 BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 1.8 liter |
| E 200 CGI BlueEFFICIENCY Coupé | benzine | 5G-Tronic 5 | 1.8 liter |
| E 250 BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 1.8 liter |
| E 250 CGI BlueEFFICIENCY Coupé | benzine | 5G-Tronic 5 | 1.8 liter |
| E 300 BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 CGI BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 350 BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 3.5 liter |
| E 500 BlueEFFICIENCY Coupé | benzine | 7G-Tronic 7 | 4.7 liter |
| E 500 Coupé | benzine | 7G-Tronic 7 | 5.5 liter |
| E 220 CDI BlueEFFICIENCY Coupé | diesel | handm. 6 | 2.1 liter |
| E 220 CDI BlueEFFICIENCY Coupé | diesel | handm. 6 | 2.1 liter |
| E 250 CDI BlueEFFICIENCY Coupé | diesel | handm. 6 | 2.1 liter |
| E 250 CDI BlueEFFICIENCY Coupé | diesel | handm. 6 | 2.1 liter |
| E 220 CDI BlueEFFICIENCY Coupé | diesel | 7G-Tronic 7 | 2.1 liter |
| E 220 CDI BlueEFFICIENCY Coupé | diesel | 5G-Tronic 5 | 2.1 liter |
| E 250 CDI BlueEFFICIENCY Coupé | diesel | 7G-Tronic 7 | 2.1 liter |
| E 250 CDI BlueEFFICIENCY Coupé | diesel | 5G-Tronic 5 | 2.1 liter |
| E 350 CDI BlueEFFICIENCY Coupé | diesel | 7G-Tronic 7 | 3.0 liter |
| E 350 CDI BlueEFFICIENCY Coupé | diesel | 7G-Tronic 7 | 3.0 liter |
| Type | Motor | Transmissie | Inhoud |
| E 200 Coupé | benzine | handm. 5 | 2.0 liter |
| E 220 Coupé | benzine | handm. 5 | 2.2 liter |
| E 320 Coupé | benzine | handm. 5 | 3.2 liter |
| E 200 Coupé | benzine | 4G-Tronic 4 | 2.0 liter |
| E 220 Coupé | benzine | 4G-Tronic 4 | 2.2 liter |
| E 320 Coupé | benzine | 4G-Tronic 4 | 3.2 liter |
| E 36 AMG Coupé | benzine | 4G-Tronic 4 | 3.6 liter |